Biofilm Testing Capabilities:
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Biofilm disinfectant efficacy testing
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Chronic wound biofilms & dressings
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Oral biofilms
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Medical devices
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Drug synergy (modified checkerboard assay)
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Biofilm in treated water systems
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Biofilm Test Methods:
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CDC Biofilm Reactor Protocol ASTM E2562 & Single Tube Method ASTM E2871
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Drip Flow Reactor Protocol E2647
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Modified Colony/Drip Flow Reactor Protocol
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Minimum Biofilm Eradication Concentration (MBEC) Testing ASTM E2799
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EPA Protocols
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Zero-Shear (Static) Biofilms
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Custom experimental design
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In-Vitro Testing
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In-Vitro Testing Capabilities:
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Time-Kill Kinetic/ Suspension Test
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MIC/MBC Testing
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Antimicrobial Effectiveness Testing
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Zone-Of-Inhibition
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Disinfectant Testing
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Medical Devices Testing
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Testing of Bound Antimicrobials
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Safety Testing
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IN-Vitro Test Methods:
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ASTM E2799
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MBEC Reactor Protocol BioScience Labs provides services for evaluation of product efficacy in the prevention and/or removal of biofilms
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ASTM E2274
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Standard Test Method for Evaluation of Laundry Sanitizers and Disinfectants
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ASTM E2562
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CDC Biofilm Reactor Protocol
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ASTM E2406
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Standard Test Method for Evaluation of Laundry Sanitizers and Disinfectants for Use in High Efficiency Washing Operations
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ASTM E2871
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Single Tube Method BioScience Labs provides services for evaluation of product efficacy in the prevention and/or removal of biofilms using in-vitro techniques
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ASTM E2197
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Standard Quantitative Disk Carrier Test Method for Determining Bactericidal, Virucidal, Fungicidal, Mycobactericidal, and Sporicidal Activities of Chemicals
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ASTM E2149
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Standard Test Method for Determining the Antimicrobial Activity of Antimicrobial Agents Under Dynamic Contact Conditions
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ASTM E2647
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Drip Flow Reactor Protocol BioScience Labs provides services for evaluation of product efficacy in the prevention and/or removal of biofilms using in-vitro techniques.
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ASTM E2362
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Standard Practice for Evaluation of Pre-saturated or Impregnated Towelettes for Hard Surface Disinfection
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ASTM E640
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Standard Test Method for Preservatives in Water-Containing Cosmetics
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ASTM E1153
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Standard Test Method for Efficacy of Sanitizers Recommended for Inanimate Non- Food Contact Surfaces
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ASTM E1054
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Standard Test Method for Evaluation of Inactivators of Antimicrobial Agents The effectiveness of antimicrobial agents incorporated into disinfectants, sanitizers, and antiseptics
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ASTM E2280
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Standard Test Method for Determining the Activity of Incorporated Antimicrobial Agent(s) in Polymeric or Hydrophobic Materials
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ASTM E2783
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Standard Test Method for Assessment of Antimicrobial Activity for Water-Miscible Compounds Using a Time-Kill Procedure
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ASTM E1671
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Resistance of Materials Used in Protective Clothing to Penetration by Blood-Borne Pathogens Using Phi-X174 Bacteriophage Penetration as a Test System
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AOAC 960.09
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Germicidal and Detergent Sanitizing Action of Disinfectants Test
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AOAC 965.13
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Disinfectants (Water) for Swimming Pools This standard test method recommended by the EPA
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AOAC 966.04
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Sporicidal Activity of Disinfectants This standard method tests the efficacy of disinfectants against spore-forming bacteria on hard surface carriers
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AOAC 955.17
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Fungicidal activity of Disinfectants' Using Trichophyton Mentagrophytes
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AOAC
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Germicidal Towelette Test
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AOAC 961.02
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Germicidal Spray Products as Disinfectants This standard test method recommended by the EPA
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AOAC 965.12
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Tuberculocidal Activity of Disinfectants
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AOAC 955.16
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Chlorine (available) in Disinfectants; Germicidal Equivalent Concentration
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AOAC 655.14, 955.15, & 964.02
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Use Dilution Method These standard methods test the efficacy of disinfectants against three standard bacteria on hard surfaces
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EN 1040
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Chemical Disinfectants and Antiseptics- Quantitative Suspension Test for the Evaluation of Basic Bactericidal Activity of Chemical Disinfectants and Antiseptics
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EP 5.1.3
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The European Pharmacopeia describes in General Text 5.1.3, the assay they recommend for testing preservative efficacy
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EN 1275
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Quantitative suspension Test for the Evaluation of Basic Fungicidal or Basic Yeasticidal Activity of Chemical Disinfectants and Antiseptics
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EN 14348
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Quantitative Suspension Test for the Evaluation of Mycobactericidal Activity of Chemical Disinfectants in the Medical Area Including Instrument Disinfectants
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EN 1276
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Quantitative Suspension Test for the Evaluation of Bactericidal Activity of Chemical Disinfectants and Antiseptics used in Food, Industrial, Domestic and Institutional Areas
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EN 13697
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Quantitative Non-Porous Surface Test for the Evaluation of Bactericidal and/or Fungicidal Activity of Chemical Disinfectants Used in Food, Industrial, Domestic and Institutional Areas
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EN 13727
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Quantitative Suspension Test for the Evaluation of Bactericidal Activity in the Medical Area
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EN 1650
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Quantitative Suspension Test for the Evaluation of Fungicidal activity of Chemical Disinfectants and Antiseptics Used in Food, Industrial, Domestic and Institutional Areas
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EN 13624
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Quantitative Suspension Test for the Evaluation of Fungicidal Activity of Chemical Disinfectants for Instruments used in the Medical Area
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OECD 435
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In Vitro Membrane Barrier Test Method for Skin Corrosion
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OECD 437
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Bovine Corneal Opacity and Permeability (BCOP) Test Method for Identifying Ocular Corrosives/Severe Irritants and Substances not Classified as Irritants
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OECD 439
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In-Vitro Skin Irritation
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OECD 492
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Reconstructed human Cornea-like Epithelium (RhCE) test method for identifying chemicals not requiring classification and labelling for eye irritation or serious eye damage
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OECD 431
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In-Vitro Skin Corrosion: Human Skin Model Test In this method
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ISO 11930
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The International Organization for Harmonization is designed for cosmetic formulations
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JIS L1902
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Determination of Antibacterial Activity of Antibacterial Materials
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USP 51
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ANTIMICROBIAL PRESERVATIVE EFFECTIVENESS TEST (PET)
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Personal Care Products Council (PCPC) M3 & M4
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AATCC 100 Antimicrobial Finishes on Textile Materials
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CLSI M07-A10
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Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically
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CLSI M11-A8
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Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Anaerobically
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CLSI M24-A2
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Susceptibility Testing of Mycobacteria, Nocardiae, and Other Aerobic Actinomycetes
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CLSI M26-A
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Methods for Determining Bactericidal Activity of Antimicrobial Agents
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CLSI M27-A3
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Method for Broth Dilution Antifungal Susceptibility Testing of Yeast
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CLSI M33-A
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Antiviral Susceptibility Testing: Herpes Simplex Virus
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CLSI M38-A2
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Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi
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CLSI M45
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Methods for Antimicrobial Dilution and Disk Susceptibility Testing of Infrequently Isolated or Fastidious Bacteria
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CLSI M100
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Performance Standards for Antimicrobial Susceptibility Testing
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Clinical/In-Vivo Testing
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Clinical/In-Vivo Testing Capabilities:
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Handwash Efficacy
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Handrub Efficacy
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Surgical Scrub Efficacy
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Preoperative, Precatheterization, or Preinjection Skin Preparations
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Product Persistence
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Product Residual Efficacy
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CHG Compatibility
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Oral Antiseptic Efficacy
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Clinical/In-Vivo Test Methods:
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ASTM E2784
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Standard Test Method for Evaluation of the Effectiveness of Handwash Formulations Using the Paper Towel (Palmar) Method of Hand Contamination
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ASTM E2011
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Standard Test Method for Evaluation of Hygienic Handwash and Handrub Formulations for Virus-Eliminating Activity Using the Entire Hand
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ASTM E2752
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Standard Guide for Evaluation of Residual Effectiveness of Antibacterial Personal Cleansing Products
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ASTM E1838
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Standard Test Method for Determining the Virus-Eliminating Effectiveness of Hygienic Handwash and Handrub Agents Using the Fingerpads of Adults
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ASTM E2613
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Standard Test Method for Determining Fungus-Eliminating Effectiveness of Hygienic Handwash and Handrub Agents Using Fingerpads of Adults
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ASTM E1174
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Standard Test Method for Evaluation of the Effectiveness of Health Care Personnel Handwash Formulations
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ASTM E1115
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Standard Test Method for Evaluation of Surgical Hand Scrub Formulations
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ASTM E2946
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Standard test method for: Determining the Bacteria-Reducing Effectiveness and Food-Handler Handwash Formulations Using Hands of Adults
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ASTM E2755
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Standard Test Method for Determining the Bacteria-Eliminating Effectiveness of Healthcare Personnel Hand Rub Formulations Using Hands of Adults
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ASTM E1173
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Standard Test Method for Evaluation of Preoperative, Precatheterization, or Preinjection Skin Preparations
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ASTM E1882
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Standard Test Method for Evaluation of Antimicrobial Formulations by the Agar patch Technique
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ASTM E2752 –
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Evaluation of Residual Effectiveness of Antibacterial Personal Cleansing Products
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ASTM E2276
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Standard Test Method for Determining the Bacteria-Eliminating Effectiveness of Hygienic Handwash and Handrub Agents Using the FIngerpads of Adults
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ASTM E2870
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Standard Test Method for Evaluating Relative Effectiveness of Antimicrobial handwashing Formulations using the Palmar Surface and Mechanical Hand Sampling
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ASTM E1327
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Standard Test Method for Evaluation of Antimicrobial Handwash Formulations by Utilizing Fingernail Regions
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EN 12791
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European Standard test method for Surgical Scrub products
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EN 1499
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European Standard test method for Hygienic Handwash (water aided) products
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EN 1500
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European Standard test method for Healthcare Personnel Hand Rub (no water) products
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PGRM Plaque Glycolysis and Regrowth Method (PGRM) is a proven clinical assay for bioavailability, retention and proportional efficacy of mouthrinses.
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Materials Testing Laboratory
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Materials Testing Capabilities:
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Absorbency
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Vapor Transfer Rate
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Material Strength
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Waterproofness
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Antibacterial activity
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Peel Adhesion
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Adhesive Strength
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Clinical/In-Vivo Test Methods:
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EN 13726-1
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(Sec. 3.2) Absorbency testing
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EN 13726-2
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MVTR testing
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ASTM D5035
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Dry Strength testing
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ASTM D5035
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Wet Strength testing
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ASTM D3330/D3330M
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Adhesive Strength testing
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EN 13726-3
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Waterproofness
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EN 13726-4
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Conformability
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ASTM D3574
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Sections E and F Tensile test and tear resistance test for urethane foam
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JIS L1902
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Testing for antibacterial activity and efficacy on textile products
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AATCC 100
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Assessment of Antibacterial Finishes on Textiles
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ASTM D903
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Peel or Stripping Strength of Adhesive Bonds
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ASTM D3330
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Peel Adhesion of Pressure Sensitive Tape
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ASTM D1876
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T-Peel Test
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ASTM D6195
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Adhesive Loop Tack Strength Test
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ASTM F2258
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Tensile Strength of Tissue Adhesives
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ASTM F2256
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Strength Properties of Tissue Adhesive by T-Peel Loading
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Virus Testing Laboratory
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Virus Lab Testing Capabilities:
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Virucidal Disinfectant Testing
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Blood Glucose Monitoring Systems: Cleaning & Disinfection Procedure Validation
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Viral Clearance
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Time-Kill Kinetics – Virucidal Efficacy Test
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Antiviral
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Virus Lab Test Methods:
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ASTM E1053
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Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Non-porous Environmental Surfaces Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Non-porous Environmental Surfaces
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ASTM E1052
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Standard Test Method to Assess the Activity of Microbicides against Viruses in Suspension
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ASTM E2197
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Standard Quantitative Disk Carrier Test Method for Determining Bactericidal, Virucidal, Fungicidal, Mycobactericidal, and Sporicidal Activities of Chemicals
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ASTM E1838
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Standard Test Method for Determining the Virus-Eliminating Effectiveness of Hygienic Handwash and Handrub Agents Using the Fingerpads of Adults
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ASTM E2011
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Standard Test Method for Evaluation of Hygienic Handwash and Handrub Formulations for Virus-Eliminating Activity Using the Entire Hand
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ASTM E2362
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Standard Practice for Evaluation of Pre-saturated or Impregnated Towelettes for Hard Surface Disinfection
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EN 14476E
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Quantitative Suspension Test for the Evaluation of Virucidal Activity in the Medical Area
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ISO 22442-3
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Medical devices utilizing animal tissues and their derivatives – Part 3: Validation of the elimination and/or inactivation of viruses…
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Cosmetic Claims Laboratory
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Cosmetic Product Testing Capabilities:
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Moisturization Testing
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Exfoliation
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Skin Texture
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Antiaging
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Barrier Properties
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Irritation
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Sensitization
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Skin color/tone
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Subjective Evaluations
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Cosmetic Product Lab Evaluation Methods:
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FCAT- Forearm Controlled Application Technique
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LCAT - Leg Controlled Application Technique
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TEWL - Trans-epidermal water loss
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CORNEOMETER - measures moisturization of the stratum corneum layer of the skin using capacitance
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VISIA CR – Evaluates Tissue Spots, Wrinkles, & UV Damage
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CHROMA METER – Measures Skin Color in Three Scales: White, Red/Green, & Blue/Yellow
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MEXAMETER - Measures Redness/Color Change
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SEBUMETER – Measures Skin Sebum Levels
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PH Meter – Measures Skin PH
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SKICON – measures the moisturization content of the stratum corneum level of the skin using high frequency conductance
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